2022
Čurillová J., Pecháčková M., Pádrtová T., Pecher D., Mascaretti Š., Jampílek J., Pašková L., Bilka F., Kováč G., Malík I. Synthesis and Critical View on Structure–Activity Relationships of N-(Substituted Phenyl)-/N-Diphenylmethylpiperazine-Based Conjugates as Antimycobacterial Agents. Appl. Sci. 2022, vol. 12, no. 1, 300, https://www.mdpi.com/2076-3417/12/1/300/pdf. [ISSN 2076-3417, IF2020 = 2.679, Q2]
Havránková E., Garaj V., Mascaretti Š., Angeli A., Soldánová Z., Kemka M., Motyčka J., Brázdová M., Csöllei J., Jampílek J., Supuran C.T. Novel 1,3,5-Triazinyl Aminobenzenesulfonamides Incorporating Aminoalcohol, Aminochalcone and Aminostilbene Structural Motifs as Potent Anti-VRE Agents, and Carbonic Anhydrases I, II, VII, IX, and XII Inhibitors. Int. J. Mol. Sci. 2022, vol. 23, no. 1, 231, https://www.mdpi.com/1422-0067/23/1/231/pdf. [ISSN 1422-0067, IF2020 = 5.923, Q1]
Razmienė, B., Vojáčková, V., Řezníčková, E., Malina, L., Dambrauskienė, V., Kubala, M., Bajgar, R., Kolářová, H., Žukauskaitė, A., Arbačiauskienė, E., Šačkus, A., Kryštof, V. (2022) Synthesis of N-aryl-2,6-diphenyl-2H-pyrazolo[4,3-c]pyridin-7-amines and their photodynamic properties in the human skin melanoma cell line G361. Bioorganic Chemistry, 119, 105570. (IF2020 = 5.275) https://doi.org/10.1016/j.bioorg.2021.105570
2021
Bíbová J., Zatloukal M., Koprna R., Spíchal L., Strnad M., New Generation of Arabidopsis thaliana Cytokinin oxidase/Dehydrogenase inhibitors Affect Shoot/Root Growth and Seed Yield In Meta-topolin: A Growth Regulator for Plant Biotechnology and Agriculture. Springer Nature Singapore Pte Ltd. 2021, s. 293-316. ISBN 978-981-15-9046-7.
Doležal K., Bryksová M., Topolin Metabolism and Its Implications for In Vitro Plant Micropropagation In Meta-topolin: A Growth Regulator for Plant Biotechnology and Agriculture. Springer Nature Singapore Pte Ltd. 2021, s. 49-58. ISBN 978-981-15-9046-7.
Empel A. and Bak A., Kozik V., Latocha M., Čížek A., Jampílek J., Suwinska K., Sochanik A., Zieba A. Towards Property Profiling: Synthesis and SAR Probing of New Tetracyclic Diazaphenothiazine Analogues. Int. J. Mol. Sci. 2021, vol. 22, no. 23, 12826. (IF = 5.923) https://www.mdpi.com/1422-0067/22/23/12826/pdf
Hrdlička J., Gucký T., Van Staden J., Novák O., Doležal K. (2021) A stable isotope dilution method for a highly accurate analysis of karrikins. Plant Methods, 17, 37. (IF = 3.974) https://doi.org/10.1186/s13007-021-00738-1
Hemelíková, N., Žukauskaitė, A., Pospíšil, T., Strnad, M., Doležal, K., Mik, V. (2021) Caged phytohormones: from chemical inactivation to controlled physiological response. Journal of Agricultural and Food Chemistry, 69, 12111. (IF = 5.279) https://doi.org/10.1021/acs.jafc.1c02018
Iškauskienė M., Kadlecová A., Voller J., Janovská L., Malinauskienė V., Žukauskaitė A., Šačkus A. (2021) Synthesis of 5-[(1H-indol-3-yl)methyl]-1,3,4-oxadiazole-2(3H)-thiones and their protective activity against oxidative stress. Archiv der Pharmazie, 354, e2100001. (IF = 3.751) https://doi.org/10.1002/ardp.202100001
Koprna R., Humplík J.F., Špíšek Z., Bryksová M., Zatloukal M., Mik V., Novák O., Nisler J., Doležal K. (2021) Improvement of tillering and grain yield by application of cytokinin derivatives in wheat and barely. Agronomy, 11, 67. ( IF=2.603) https://doi.org/10.3390/agronomy11010067
Koprna R., Zatloukal M., Doležal K., Topolins and Related Compounds: Uses in Agriculture In Meta-topolin: A Growth Regulator for Plant Biotechnology and Agriculture. Springer Nature Singapore Pte Ltd. 2021, s. 317-328, ISBN 978-981-15-9046-7.
Pařízková B., Žukauskaitė A., Vain T., Grones P., Raggi S., Kubeš M.F., Kieffer M., Doyle S.M., Strnad M., Kepinski S., Napier R., Doležal K., Robert S., Novák O. (2021) New fluorescent auxin probes visualise tissue-specific and subcellular distributions of auxin in Arabidopsis. New Phytologist, 230, 535. (IF = 10.152) https://doi.org/10.1111/nph.171833
Plíhalová L., Synthesis and Chemistry of Meta-Topolin and Related Compounds In: Meta-topolin: A Growth Regulator for Plant Biotechnology and Agriculture. Springer Nature Singapore Pte Ltd. 2021, s. 11-22 ISBN 978-981-15-9046-7.
Pospíšil, J.; Konrádová, D.; Strnad, M.,Antileishmanial Activity of Lignans, Neolignans, and Other Plant Phenols. In Progress in the Chemistry of Organic Natural Products 115; Springer International Publishing, 2021; pp 115–176. https://doi.org/10.1007/978-3-030-64853-4_3
Razmienė, B., Řezníčková, E., Dambrauskienė, V., Ostruszka, R., Kubala, M., Žukauskaitė, A., Kryštof, V., Šačkus, A., Arbačiauskienė, E. Synthesis and antiproliferative activity of 2,4,6,7-tetrasubstituted-2H-pyrazolo[4,3-c]pyridines. Molecules, 26, 6747. (IF = 4.412) https://doi.org/10.3390/molecules26216747
Samakovli, D., Roka, L., Dimopoulou, A., Plitsi, P.K., Žukauskaitė, A., Georgopoulou P., Novák, O., Milioni, D., Hatzopoulos, P. (2021) HSP90 affects root growth in Arabidopsis by regulating the polar distribution of PIN1. New Phytologist, 231, 1814. (IF = 10.152) https://doi.org/10.1111/nph.17528
Zálešák F., Kováč O., Lachetová E., Šťastná N., Pospíšil J. (2021) Unified Approach to Benzo[d]thiazol-2-yl-Sulfonamides. Journal of Organic Chemistry 86(17): 11291–11309. (IF = 4.354) DOI: 10.1021/acs.joc.1c00317
Zhang C., Žukauskaitė A., Petřík I., Pěnčík A., Hönig M., Grúz J., Široká J., Novák O., Doležal K. (2021) In situ characterisation of phytohormones from wounded Arabidopsis leaves using desorption electrospray ionisation mass spectrometry imaging. Analyst, 146, 2653. (IF = 4.616) https://doi.org/10.1039/D0AN02118K
2020
Antoniadi I., Novák O., Gelová Z., Johnson A., Plíhal O., Simerský R., Mik V., Vain T., Mateo-Bonmatí E., Karady M., Pernisová M., Plačková L., Opassathian K., Hejátko J., Robert S., Friml J., Doležal K., Ljung K., Turnbull C. (2020) Cell-surface receptors enable perception of extracellular cytokinins. Nature Communications, 11, 4284. (IF = 12.121) https://doi.org/10.1038/s41467-020-17700-9
Aremu A.O., Fawole O.A., Makunga N.P., Masondo N.A., Moyo M., Buthelezi N.M.D., Amoo S.O., Spíchal L., Doležal K. (2020) Applications of cytokinins in horticultural fruit crops: Trends and future prospects. Biomolecules, 10, 1222. (IF = 4.694) https://doi.org/10.3390/biom10091222
Bryksová M., Dabravolski S., Kučerová Z., Zavadil Kokáš F., Špundová M., Plíhalová L., Takáč T., Grúz, J., Hudeček M., Hlousková V., Koprna R., Novák O., Strnad M., Plíhal O., Doležal K. (2020) Aromatic cytokinin arabinosides promote PAMP-like responses and positively regulate leaf longevity. ACS Chemical Biology, 15, 1949. (IF = 4.434) https://doi.org/10.1021/acschembio.0c00306
Bryksová M., Hybenová A., Hernandíz A.E., Novák O., Pěnčík A., Spíchal L., De Diego N., Doležal K. (2020) Hormopriming to migrate abiotic stress effects: A case study of N9-substituted cytokinin derivatives with a fluorinated carbohydrate moiety. Frontiers in Plant Science, 11, 599228. (IF = 4.402) https://doi.org/10.3389/fpls.2020.599228
Gupta S., Hrdlička J., Ngoroyemoto N., Nemahunguni N.K., Gucký T., Novák O., Kulkarni M.G., Doležal K., Van Staden J. (2020) Preparation and standardisation of smoke-water for seed germination and plant growth stimulation. Journal of Plant Growth Regulation, 39, 338. (IF = 2.672) https://doi.org/10.1007/s00344-019-09985-y
Hlatshwayo N.A., Amoo S.O., Olowoyo J.O., Doležal K. (2020) Efficient micropropagation protocol for the conservation of the endangered Aloe peglerae, an ornamental and medicinal species. Plants, 9, 506. (IF = 3.182) https://doi.org/10.3390/plants9040506
Hlophe N.P., Aremu A.O., Doležal K., Van Staden J., Finnie J.F. (2020) Cytokinin-facilitated plant regeneration of three Brachystelma species with different conservation status. Plants, 9, 1657. (IF = 3.182) https://doi.org/10.3390/plants9121657
Kováč O., Zálešák F., Bon D.J.-Y.D., Roiser L., Baar L.V., Waser M., Pospíšil J. (2020) Trisubstituted highly activated benzo[d]thiazol-2-yl-sulfone-containing olefins as building blocks in organic synthesis. Journal of Organic Chemistry, 85, 7192. (IF = 4.335) https://doi.org/10.1021/acs.joc.0c00571
Králová P., Maloň M., Pospíšil J., Soural M. (2020) Rearrangement of threonine and serine-based N-(3-phenylprop-2-yn-1-yl) sulfonamides yields chiral pyrrolidin-3-ones. Journal of Organic Chemistry, 5, 985. (IF = 4.335) https://doi.org/10.1021/acs.joc.9b02932
Kubiasová K., Montesinos J.C., Šamajová O., Nisler J., Mik V., Semerádová H., Plíhalová L., Novák O., Marhavý P., Cavallari N., Zalabák D., Berka K., Doležal K., Galuszka P., Šamaj J., Strnad M, Benková E., Plíhal O., Spíchal L. (2020) Cytokinin fluoroprobe reveals multiple sites of cytokinin perception at plasma membrane and endoplasmic reticulum. Nature Communications, 11, 4285. (IF = 13.610) https://doi.org/10.1038/s41467-020-17949-0
Kučerová Z., Rác M., Mikulík J., Plíhal O., Pospíšil P., Bryksová M., Sedlářová M., Doležal K., Špundová M. (2020) The anti-senescence activity of cytokinin arabinosides in wheat and Arabidopsis in negatively correlated with ethylene production. International Journal of Molecular Sciences, 21, 8109. (IF = 5.556) https://doi.org/10.3390/ijms21218109
Mathieu A.S., Dobrev P.I., Tarkowská D., Pospíšil J., Motyka V., Quinet M., Lutts S. (2020) Phytohormone profile and CiFL1 expression in young seedlings of Cichorium intybus L. var sativum exposed to high temperature in relation to vernalization and de-vernalization processes. Enviromental and Experimental Botany, 178, 104127. (IF = 4.027) https://doi.org/10.1016/j.envexpbot.2020.104127
Matušková V., Zatloukal M., Voller J., Grúz J., Pěkná Z., Briestenská K., Mistríková J., Spíchal L., Doležal K., Strnad M. (2020) New aromatic 6-substituted 2 '-deoxy-9-β-D-ribofuranosylpurine derivatives as potential plant growth regulators. Bioorganic & Medicinal Chemistry, 28, 115230. (IF = 3.073) https://doi.org/10.1016/j.bmc.2019.115230
Milišiūnaitė V., Kadlecová A., Žukauskaitė A., Doležal K., Strnad M., Voller J., Arbačiauskienė E., Holzer W., Šačkus A. (2020) Synthesis and anthelmintic activity of benzopyrano[2,3-c]pyrazol-4(2H)-one derivatives. Molecular Diversity, 24, 1025. (IF = 2.013) https://doi.org/10.1007/s11030-019-10010-3
Nisler J., Kopečný D., Pěkná Z., Končitíková R., Koprna R., Murvanidze N., Werbrouck S.P.O., Havlíček L., De Diego N., Kopečná M., Wimmer Z., Biozzo P., Moréra S., Zalabák D., Spíchal l., Strnad M. (2020) Diphenylurea-derived cytokinin oxidase/dehydrogenase inhibitors for biotechnology and agriculture. Journal of Experimental Botany, 72, 355. (IF = 5.908) https://doi.org/10.1093/jxb/eraa437
Omoarelojie L.O., Kulkarni M.G., Finnie J.F., Pospíšil T., Strnad M., Van Staden J. (2020) Synthetic strigolactone (rac-GR24) alleviates the adverse effects of heat stress on seed germination and photosystem II function in lupine seedlings. Plant Physiology and Biochemistry, 155, 965. (IF = 3.720) https://doi.org/10.1016/j.plaphy.2020.07.043
Pospíšil, J. 1-(Phenylsulfonyl)-3-oxabicyclo[3.1.0]hexan-2-one” Pospíšil, J. In Encyclopedia of Reagents for Organic Synthesis; Major Reference Works; Wiley Online Library, New Jersey, 2020, pp 1–4. https://doi.org/10.1002/047084289X.rn02295
Šachlevičiūtė U., Varvuolytė G., Bieliauskas A., Kleizienė N., Žukauskaitė A., Šačkus A. (2020) 3,3,3′,3′-Tetramethyl-2,2′-diphenyl-3H,3′H-5,5′-biindole. Molbank, 1146, 1. (IF = 0.450) https://doi.org/10.3390/M1146
Tan S., Abas M., Verstraeten I., Glanc M., Molnár G., Hajný J., Lasák P., Petřík I., Russinova E., Petrášek J., Novák O., Pospíšil J., Friml J. (2020) Salicylic acid targets protein phosphatase 2A to attenuate growth in plants. Current Biology, 30, 381. (IF = 9.601) https://doi.org/10.1016/j.cub.2019.11.058
Vacek J., Zatloukalová M., Vrba J., De Vleeschouwer F., De Proft F., Obluková M., Sokolová R., Pospíšil J (2020) Diferulate: A highly effective electron donor. Journal of Electroanalytical Chemistry, 869, 113950. (IF = 3.807) https://doi.org/10.1016/j.jelechem.2020.113950
Varvuolytė G., Malina L., Bieliauskas A., Hošíková B., Simerská H., Kolářová H., Kleizienė N., Kryštof V., Šačkus A., Žukauskaitė A (2020) Synthesis and photodynamic properties of pyrazole-indole hybrids in the human skin melanoma cell line G361. Dyes and Pigments, 183, 108666. (IF = 4.613) https://doi.org/10.1016/j.dyepig.2020.108666
Vylíčilová H., Bryksová M., Matušková V., Doležal K., Plíhalová L., Strnad M. (2020) Naturally occurring and artificial N9-cytokinin conjugates: from synthesis to biological activity and back. Biomolecules, 10, 832. (IF = 4.694) https://doi.org/10.3390/biom10060832
Patenty
2021
CZ 308881: Doležal K, Plíhalová L, Vylíčilová H, Zatloukal M, Plíhal O, Voller J, Strnad M: 6-aryl-9-glykosylpuriny a jejich použití, Univerzita Palackého v Olomouci (23/6/2021).
CZ 308800: Gonzales, Mik, Bucharová, Grúz, Kaňovský, Strnad, Zatloukal: Heterocyklické dusíkaté deriváty purinu, farmaceutické přípravky obsahující tyto deriváty a jejich použití při neuroprotekci (14/4/2021)
2020
US 10774084: Adenine derivatives and their use as UV-photoprotective agents, UPOL, Hönig M, Plíhalová L, Doležal K, Voller J, Strnad M, Spíchal L, Vostálová J, Rajnochová Svobodová A, Ulrichová J, Kadlecová A, Plíhal O, uděleno: 15/9/2020
US 10550144: 6-aryl-9-glykosylpurines and use thereof, UPOL, Doležal K, Plíhalová L, Vylíčilová H, Zatloukal M, Plíhal O, Voller J, Strnad M, Van Staden Johannes, Ponnusamy Baskaran, Aloka Kumari, Adeyemi Oladapo Aremu, uděleno: 4/2/2020
US 10662194: Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress, UPOL, Zatloukal M, Plíhalová L, Klásková J, Spíchal L, Koprna R, Doležal K, Strnad M, uděleno: 26/5/2020
EP 3229772: 6-aryl-9-glycosylpurines and use thereof, UPOL, Doležal K, Plíhalová L, Vylíčilová H, Zatloukal M, Plíhal O, Voller J, Strnad M, Van Staden J, Baskaran P, Kumari A, Aremu AO, uděleno: 29/4/2020
EP3233860: Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress, Zatloukal M, Plíhalová L, Klásková J, Spíchal L, Koprna R, uděleno. 29/1/2020
SG 11201704019T: 6-aryl-9-glykosylpurines and use thereof, Doležal K, Plíhalová L, Vylíčilová H, Zatloukal M, Plíhal O, Voller J, Strnad M, Bryksová M, Vostálová J, Rajnochová Svobodová A, Ulrichová J, Spíchal L, uděleno: 24/6/2020
2019
CZ307868: 9- (2-Oxacycloalkyl) -9H-purine-2,6-diamine derivatives, preparations containing these derivatives and their use, Bíbová J, Mik V, Zatloukal M, Plíhalová L, Grúz J, Spíchal L, Doležal K, Strnad M, uděleno: 29/5/2019.
CZ307722: Adenine derivatives and their use as UV-photoprotective agents/ Adeninové deriváty a jejich použití, Honig M, Plíhalová L, Doležal K, Voller J, Strnad M, Spíchal L, Vostálová J, Rajnochová Svobodová A, Ulrichová J, Kadlecová A, Plíhal O, uděleno: 13/2/2019
2018
US10100077: 6-aryl-9-glycosylpurines and use thereof, Doležal K, Plíhalová L, Vylíčilová H, Zatloukal M, Plíhal O, Voller J, Strnad M, Bryksová M, Vostálová J, Rajnochová Svobodová A, Ulrichová J, Spíchal L, uděleno: 2018.
US10093675: 6,8-disubstituted-9-(heterocyclyl)purines, compositions containing these derivatives and their use in cosmetic and medicinal applications, Zahajská L, Nisler J, Kadlecová A, Zatloukal M, Grúz J, Voller J, Doležal K, Strnad M, uděleno 2018.
Registrace rostlinných přípravků
Aucyt Start (2018) – pomocný rostlinný přípravek, registrant – ÚKZÚZ, evidenční číslo R9445, registrační číslo: 4615.
Salis (2019) – pomocný rostlinný přípravek, registrant – ÚKZÚZ, evidenční číslo R10222, registrační číslo: 4672.
VegetUP (2020) – pomocný rostlinný přípravek, registrant – ÚKZÚZ, evidenční číslo R10345, registrační číslo: 4988.