2025

Golovina E, Kokavec J, Kazantsev D, Yurikova O, Bajecny M, Savvulidi FG, Simersky R, Lenobel R, Tost J, Herynek V, Sefc L, Sebela M, Klener P, Zemanova Z, Stopka T, Vargova KS. Deficiency of miR-155 in leukemic B-cells results in cell cycle arrest and deregulation of MIR155HG/TP53INP1/CDKN1A/CCND1 network. Arch Med Res. 2024 Nov 25;56(3):103124. doi: 10.1016/j.arcmed.2024.103124. Epub ahead of print. PMID: 39591901.

Jampílek, J.; Kráľová, K. Nanotoxicity effects of metal oxide nanoparticles on aquatic and soil ecosystems. In: Nanoscience and Soil-Water Interaction in Agroecosystem. Kamel A. Abd-Elsalam, Feng Wang, Muhammad Zahid (Eds.). CRC Press/Taylor & Francis Group, Boca Raton, FL, USA, 2025, Chapter 5, pp. 79-129. [ISBN 978-1-032-55156-2]

Kos, J.; Strhársky, T.; Tosso, R.; Gutierrez, L.; Kos, D.; Juřica, J.; Zendulka, O.; Peš, O.; Gregorová, J.; Degotte, G.; Goněc, T.; Oravec, M.; Vojáčková, V.; Kryštof, V.; Čížek, A.; Francotte, P.; Frederich, M.; Jampílek, J.; Enriz, R.D. Trifluoromethylcinnamanilides - Effective Dual Inhibitors of Mycobacterium smegmatis and Plasmodium falciparum. Bioorg. Chem. 2025, 154, 107957. https://doi.org/10.1016/j.bioorg.2024.107957.

Maková, B., Mik, V., Lišková, B., Drašarová, L., Medvedíková, M., Hořínková, A., Vojta, P., Zatloukal, M., Plíhalová, L., Hönig, M., Doležal, K., Forejt, K., Oždian, T., Hajdúch, M., Strnad, M., Voller, J. (2025) Correction of aberrant splicing of ELP1 pre-mRNA by kinetin derivatives – A structure activity relationship study. European Journal of Medicinal Chemistry, 284, 117176. https://doi.org/10.1016/j.ejmech.2024.117176

2024

Bieleszová, K., Hladík, P., Kubala, M., Napier, R., Brunoni, F., Gelová, Z., Fiedler, L., Kulich, I., Strnad, M., Doležal, K., Novák, O., Friml, J., Žukauskaitė, A. New fluorescent auxin derivatives: anti-auxin activity and accumulation patterns in Arabidopsis thaliana. Plant Growth Regulation 2024, 102, 589-602. https://doi.org/10.1007/s10725-023-01083-0

Bon, D.J.-.-Y.D., Chrenko, D., Kováč, O., Ferugová, V., Lasák, P., Fuksová, M., Zálešák, F. and Pospíšil, J. (2024), Julia-Kocienski-Like Connective C−C and C=C Bond-Forming Reaction. Adv. Synth. Catal.. https://doi.org/10.1002/adsc.202301054

Fryčak, T., Furst, T., Koprna, R., Špíšek, Z., Miřijovský, J., & Humplík, J. F. (2024). Crop growth dynamics: Fast automatic analysis of LiDAR images in field-plot experiments by specialized software ALFA. PLoS ONE, 19(1 JANUARY), 1–11. https://doi.org/10.1371/journal.pone.0297153

Gazdík, Z., Vymětal, T., Koprna, R., Lojková, L., & Cerkal, R. (2023). Control of malting barley Fusarium head blight by bioagents. KVASNY PRUMYSL, 69(3), 747–754. doi.org/10.18832/kp2023.69.747

Chamrád, I., Simerský, R., Lenobel, R., & Novák, O. (2024). Exploring affinity chromatography in proteomics: A comprehensive review. Analytica Chimica Acta, March. https:doi.org/10.1016/j.aca.2024.342513

Chrenko, D.; Pospíšil, J. Latest Developments of the Julia–Kocienski Olefination Reaction: Mechanistic Considerations. Molecules 2024, 29, 2719. doi.org/10.3390/molecules29122719

Jampílek, J. a Kráľová, K. Fungal volatile organic compounds. In: Fungal Secondary Metabolites: Synthesis and Applications in Agroecosystem. Kamel Ahmed Abd-Elsalam, Heba Ibrahim Mohamed (Eds.). Elsevier, Amsterdam, Netherlands, 2024, Chapter 20, pp. 399-426. [ISBN 978-0-323-95241-5]

Niziołek, K.; Słota, D.; Sadlik, J.; Kosińska, Ed.; Korzeń, K.; Jampílek, J.; Sobczak-Kupiec, A. Sideritis raeseri—Modified Coatings on Ti-6Al-4V as a Carrier for Controlled Delivery Systems of Active Substances. Materials 2024, vol. 17, no. 10, 2250. https://doi.org/10.3390/ma17102250

Pindjaková, D.; Mascaretti, Š.; Hricovíniová, J.; Hošek, J.; Gregorová, J.; Kos, J.; Čížek, A.; Hricovíniová, Z.; Jampílek, J. Critical view on antimicrobial, antibiofilm and cytotoxic activities of quinazolin-4(3H)-one derived Schiff bases and their Cu(II) complexes. Heliyon 2024, vol. 10, no. 7, e29051. doi: 10.1016/j.heliyon.2024.e29051

Słota, D.; Jampílek, J.; Sobczak-Kupiec, A. Targeted Clindamycin Delivery Systems: Promising Options for Preventing and Treating Bacterial Infections Using Biomaterials. Int. J. Mol. Sci. 2024, vol. 25, no. 8, 4386, https://doi.org/10.3390/ijms25084386.

2023

Bigot, S., Fuksová, M., Martínez, J.-P., Lutts, S., & Quinet, M. (2023). Sodium and chloride accumulation and repartition differed between the cultivated tomato (Solanum lycopersicum) and its wild halophyte relative Solanum chilense under salt stress. Scientia Horticulturae, 321, 112324. https://doi.org/10.1016/j.scienta.2023.112324

Brunoni, F., Pěnčík, A., Žukauskaitė, A., Ament, A., Kopečná, M., Collani, S., Kopečný, D., Novák, O. Amino acid conjugation of oxIAA is a secondary metabolic regulation involved in auxin homeostasis. New Phytologist, 2023, 238, 2264-2270. https://doi.org/10.1111/nph.18887  

Dzedulionytė, K., Fuxreiter, N., Schreiber-Brynzak, E, Žukauskaitė, A., Šačkus, A., Pichler, V., Arbačiauskienė, E. Pyrazole-based lamellarin O analogues: synthesis, biological evaluation and structure–activity relationships. RSC Advances, 2023, 13, 7897-7912. https://doi.org/10.1039/D3RA00972F

Gupta, S., Bhattacharyya, P., Kulkarni, M. G. and Doležal, K. (2023) Editorial: Growth regulators and biostimulants: upcoming opportunities. Front. Plant Sci. 14 doi.org/10.3389/fpls.2023.1209499.

Hladík, P., Petřík, I., Žukauskaitė, A., Novák, O., Pěnčík, A. Metabolic profiles of 2-oxindole-3-acetyl-amino acid conjugates differ in various plant species. Frontiers in Plant Science, 2023, 14:1217421. https://doi.org/10.3389/fpls.2023.1217421

Hönig, M., Roeber, V. M., Schmülling, T. and Cortleven, A. (2023) Chemical priming of plant defense responses to pathogen attacks. 1–21. https://doi.org/10.3389/fpls.2023.1146577.

Hrdoušek, V., Špíšek, Z., Krška, B., Šedivá, J., Bakay, L. “Service Tree – the Tree for a New Europe” (2023) ISBN 978-80-87387-80-1

Hricovíni, M. and Jampílek, J. Chemistry towards Biology. Int. J. Mol. Sci. 2023, vol. 24, no. 4, 3998, https://doi.org/10.3390/ijms24043998. 

Hudeček, M., Nožková, V., Plíhalová, L. and Plíhal, O. (2023) Plant hormone cytokinin at the crossroads of stress priming and control of photosynthesis. Front. Plant Sci. 13, 1–10. https://doi.org/10.3389/fpls.2022.1103088.

Kaźmierczak, A., Tarkowská, D., Plačková, L., Doniak, M., Doležal, K. Hormonal crosstalk controls cell death induced by kinetin in roots of Vicia faba ssp. minor seedlings. Sci Rep. 2023 Jul 19;13(1):11661. doi: 10.1038/s41598-023-38641-5.

Koníčková, D., Menšíková, K., Klíčová, K., Chudáčková, M., Kaiserová, M., Přikrylová, H., Otruba, P., Nevrlý, M., Hluštík, P., Hényková, E., Kaleta, M., Friedecký, D., Matěj, R., Strnad, M., Novák, O., Plíhalová, L., Rosales, R., Colosimo, C. and Kaňovský, P. (2023) Cerebrospinal fluid and blood serum biomarkers in neurodegenerative proteinopathies : A prospective , open , cross- ­ correlation study. 1–15] doi.org/10.1111/jnc.15944.

Králová, K.  and Jampílek, J. Applications of nanomaterials in plant disease management and protection. In: Nanotechnology in Agriculture and Agroecosystems. Avinash P. Ingle (Ed). Elsevier, Amsterdam, Netherlands, 2023, Chapter 10, pp. 239-296, https://doi.org/10.1016/B978-0-323-99446-0.00013-1. [ISBN 978-0-323-99446-0

Králová, K. and Jampílek, J. Effects of nanoparticles/nanotubes on plant growth. In: The Impact of Nanoparticles on Agriculture and Soil. Nar Singh Chauhan, Sarvajeet Singh Gill (Eds.). Academic Press & Elsevier, London, UK, 2023, Chapter 10, 183-237. [ISBN 978-0-323-91703-2]

Prerostova, S., Rezek, J., Jarosova, J., Lacek, J., Dobrev, P., Marsik, P., Gaudinova, A., Knirsch, V., Dolezal, K., Plihalova, L., Vanek, T., Kieber, J. and Vankova, R. (2023) Cytokinins act synergistically with heat acclimation to enhance rice thermotolerance affecting hormonal dynamics, gene expression and volatile emission. Plant Physiol. Biochem. 198, 107683. https://doi.org/https://doi.org/10.1016/j.plaphy.2023.107683

Skalický, V., Antoniadi, I., Pěnčík, A., Chamrád, I., Lenobel, R., Kubeš, M.F., Zatloukal, M., Žukauskaitė, A., Strnad, M., Ljung, K., Novák, O. Fluorescence-activated multi-organelle mapping of subcellular plant hormone distribution. The Plant Journal, 2023, 116, 1825–1841, https://doi.org/10.1111/tpj.16456  

Słota, D.; Pi˛etak, K.; Florkiewicz, W.; Jampílek, J.; Tomala, A.; Urbaniak, M.M.; Tomaszewska, A.; Rudnicka, K.; Sobczak-Kupiec, A. Clindamycin-Loaded Nanosized Calcium Phosphates Powders as a Carrier of Active Substances. Nanomaterials 2023, 13, 1469. doi.org/10.3390/ nano13091469

Słota, D., Piętak, K., Jampilek, J. and Sobczak-Kupiec, A. (2023) Polymeric and Composite Carriers of Protein and Non-Protein Biomolecules for Application in Bone Tissue Engineering. Materials (Basel). 16, 2235. https://doi.org/10.3390/ma16062235.

Urbonavičius, A., Krikštolaitytė, S., Bieliauskas, A., Solovjova, J., Žukauskaitė, A., Arbačiauskienė, E., Šačkus, A. Synthesis and Characterization of New Pyrano[2,3-c]pyrazole Derivatives as 3-Hydroxyflavone Analogues. Molecules 2023, 28, 6599. https://doi.org/10.3390/molecules28186599

Vaňková, R., Burketová, L., Brzobohatý, B., Černý, M., Hafidh, S., Hejátko, J., Honys, D., Hoyerová, K., Juříček, M., Martinec, J., Moravec, T., Pečenková, T., Petrášek, J., Pospíšil, J., Retzer, K., Robert, H. S., Štorchová, H., Vaněk, T., Žárský, V. Responses to abiotic and biotic stresses - from the cellular level to fruit development - contributions of the Czech Centre for Experimental Plant Biology. Biologia Plantarum, 2023, 67, 166–174. https://doi.org/10.32615/bp.2023.028

Vlčko, T., Tarkowská, D., Široká, J., Pěnčík, A., Simerský, R., Chamrád, I., Lenobel, R., Novák, O. and Ohnoutková, L. (2023) Hormone profiling and the root proteome analysis of itpk1 mutant seedlings of barley (Hordeum vulgare) during the red-light induced photomorphogenesis. Environ. Exp. Bot. 213, 105428] doi.org/10.1016/j.envexpbot.2023.105428.

Zebrowski P., Rösel K., Chrenko D., Pospíšil J., Waser M. Enantioselective beta-selective addition of isoxazolidin-5-ones to allenoates catalyzed by quaternary ammonium salts. Synthesis, 2023, 55, 1706-1713. DOI: 10.1055/a-1948-5493

Žukauskaitė, A., Saiz-Fernández, I., Bieleszová, K., Iškauskienė, M., Zhang, C., Smýkalová, I., Dzedulionytė, K., Kubeš, M.F., Sedlářová, M., Pařízková, B., Pavlović, I., Vain, T., Petřík, I., Malinauskienė, V., Šačkus, A., Strnad, M., Robert, S., Napier, R., Novák, O., Doležal, K. New PEO-IAA-inspired anti-auxins: synthesis, biological activity and possible application in hemp (Cannabis Sativa L.) micropropagation. Journal of Plant Growth Regulation, 2023, 42, 7547–7563, https://doi.org/10.1007/s00344-023-11031-x 

2022

Abdouli D, Plačková L, Doležal K, Bettaieb T, Werbrouck SPO. Topolin cytokinins enhanced shoot proliferation, reduced hyperhydricity and altered cytokinin metabolism in Pistacia vera L. seedling explants. Plant Sci. 2022 Jun 15;322:111360. doi: 10.1016/j.plantsci.2022.111360. Epub ahead of print. PMID: 35716901

Adamec L, Plačková L, Doležal K. Cytokinins and auxins in organs of aquatic carnivorous plants: what do they reflect? Ann Bot. 2022 Oct 10:mcac122. doi: 10.1093/aob/mcac122. Epub ahead of print. PMID: 36215097.

Amoo S.O., Hlatshwayo N.A., Doležal K, Olowoyo J.O. Seed germination and in vitro propagation of three threatened endemic South African Aloe species, South African Journal of Botany, Volume 147, 2022, Pages 1214-1220, ISSN 0254-6299, https://doi.org/10.1016/j.sajb.2022.04.033.

Antoniadi I, Mateo-Bonmatí E, Pernisová M, Brunoni F, Antoniadi M, Villalonga MG, Ament A, Karády M, Turnbull C, Doležal K, Pěnčík A, Ljung K, Novák O. IPT9, a cis-zeatin cytokinin biosynthesis gene, promotes root growth. Front Plant Sci. 2022 Oct 14;13:932008. doi: 10.3389/fpls.2022.932008. PMID: 36311087; PMCID: PMC9616112.

Čurillová J., Pecháčková M., Pádrtová T., Pecher D., Mascaretti Š., Jampílek J., Pašková L., Bilka F., Kováč G., Malík I. Synthesis and Critical View on Structure–Activity Relationships of N-(Substituted Phenyl)-/N-Diphenylmethylpiperazine-Based Conjugates as Antimycobacterial Agents. Appl. Sci. 2022, vol. 12, no. 1, 300, https://www.mdpi.com/2076-3417/12/1/300/pdf. [ISSN 2076-3417, IF₂₀₂₁ = 2.838]

Gámez-Arcas S, Muñoz FJ, Ricarte-Bermejo A, Sánchez-López ÁM, Baslam M, Baroja-Fernández E, Bahaji A, Almagro G, De Diego N, Doležal K, Novák O, Leal-López J, León Morcillo RJ, Castillo AG, Pozueta-Romero J. Glucose-6-P/phosphate translocator2 mediates the phosphoglucose-isomerase1-independent response to microbial volatiles. Plant Physiol. 2022 Sep 16:kiac433. doi: 10.1093/plphys/kiac433. Epub ahead of print. PMID: 36111879.

Goněc T, Pindjaková D, and Vráblová L, Strhárský T, Michnová H, Kauerová T, Kollár P, Oravec M, Jendrzejewska I, Čížek A, Jampílek J. Antistaphylococcal Activities and ADME-Related Properties of Chlorinated Arylcarbamoylnaphthalenylcarbamates. Pharmaceuticals 2022, vol. 16, no. 6, 715, https://www.mdpi.com/1424-8247/15/6/715/pdf. [ISSN 1424-8247, IF₂₀₂₁ = 5.215]

Gupta, S., Doležal, K., Kulkarni, M.G. et al. Role of non-microbial biostimulants in regulation of seed germination and seedling establishment. Plant Growth Regul 97, 271–313 (2022). doi.org/10.1007/s10725-021-00794-6 (IF₂₀₂₁ = 3.260)

Gupta S, Van Staden J, Dolezal K. An understanding of the role of seed physiology for better crop productivity and food security, Plant Growth Regulation, 2022, doi: 10.1007/s10725-022-00827-8

Iakovenko RO, Chrenko D, Kristek J, Desmedt E, Zálešák F, De Vleeschouwer F, Pospíšil J. Heteroaryl sulfonamide synthesis: scope and limitations. Org Biomol Chem. 2022 Apr 13;20(15):3154-3159. doi: 10.1039/d2ob00345g. PMID: 35343994 (IF₂₀₂₁ = 3.876)

Jampílek J, Králová K. Advances in Nanostructures for Antimicrobial Therapy. Materials 2022, vol. 15, no. 7, 2388, https://www.mdpi.com/1996-1944/15/7/2388/pdf. [ISSN 1996-1944, IF₂₀₂₁ = 3.748] + Cover 2022, vol 15, no. 7: https://www.mdpi.com/1996-1944/15/7

Jampílek J, Králová K. Advances in Biologically Applicable Graphene-Based 2D Nanomaterials. Int. J. Mol. Sci. 2022, vol. 23, no. 11, 6253, https://www.mdpi.com/1422-0067/23/11/6253/pdf. [ISSN 1422-0067, IF₂₀₂₁ = 6.208]

Jampílek J. Drug Repurposing to Overcome Microbial Resistance. Drug Discov. Today 2022, vol. 27, no. 7, 2028-2041. [ISSN 1359-6446, IF₂₀₂₁ = 8.369]

Jampílek J, Králová K. Biopesticides for management of arthropod pests and weeds. In: Biopesticides: Development, Production, and Application. Amitava Rakshit, Vijay Singh Meena, P.C. Abhilash, B.K. Sarma, H.B. Singh, Leonardo F. Fraceto, Manoj Parihar, Anand Kumar Singh (Eds.). Woodhead Publishing & Elsevier, Duxford, UK, 2022, Chapter 10, 133-158. [ISBN 978-0-12-823355-9] (87.7 standard pages) 

Jampílek J, Králová K. Impact of copper-based nanoparticles on economically important plants. In: Copper Nanostructures: Next-Generation of Agrochemicals for Sustainable Agroecosystems. Kamel Ahmed Abd-Elsalam (Ed.). Elsevier, Amsterdam, Netherlands, 2022, Part 3, Chapter 13, pp. 293-339. [ISBN 978-0-12-823833-2] (84.9 standard pages) 

Jampílek J, KráĽová K. Anticancer Applications of Essential Oils Formulated into Lipid-based Delivery Nanosystems. Pharmaceutics 2022, vol. 14, no. 12, 2681, https://www.mdpi.com/1999-4923/14/12/2681/pdf. [ISSN 1999-4923, IF₂₀₂₁ = 6.525]

Jorda R, Havlicek L, Perina M, Vojackova V, Pospisil T, Djukic S, Skerlova J, Gruz J,Renesova N, Klener P, Rezacova P, Strnad M, Krystof V. 3,5,7-Substituted Pyrazolo[4,3-d]Pyrimidine Inhibitors of Cyclin-Dependent Kinases and Cyclin K Degraders. JOURNAL OF MEDICINAL CHEMISTRY, doi: 10.1021/acs.jmedchem.1c02184

Kiesel-Nawrot E, Pindjaková D, Latocha M, Bak A, Kozik V, Suwinska K, Sochanik A, Čížek A, Jampílek J and Zieba A. Design, Synthesis and Antimicrobial Properties of New Tetracyclic Quinobenzothiazine Derivatives. Int. J. Mol. Sci. 2022, vol. 23, no. 23, 15078, https://www.mdpi.com/1422-0067/23/23/15078/pdf. [ISSN 1422-0067, IF₂₀₂₁ = 6.208]

Klos D, Dušek M, Samol'ová E, Zatloukal M, Nožková V, Nesnas N, Plačková L, Koprna R, Spíšek Z, Vylíčilová H, Plíhal O, Doležal K, Voller J, Kadlecová A, Strnad M, Plíhalová L. New Water-Soluble Cytokinin Derivatives and Their Beneficial Impact on Barley Yield and Photosynthesis. J Agric Food Chem. 2022 Jun 15;70(23):7288-7301. doi: 10.1021/acs.jafc.2c00981. Epub 2022 Jun 6. PMID: 35658447. (IF₂₀₂₁ = 5.895)

Kos J, Degotte G, Pindjakova D, Strharsky T, Jankech T, Gonec T, Francotte P, Frederich M, Jampilek J. Insights into Antimalarial Activity of N-Phenyl-Substituted Cinnamanilides. Molecules. 2022; 27(22):7799. doi.org/10.3390/molecules27227799 [ISSN 1420-3049, IF₂₀₂₁ = 4.927]

Králová K, Jampílek J. Metal- and metalloid-based nanofertilizers and nanopesticides for advanced agriculture. In: Inorganic Nanopesticides and Nanofertilizers: A View from the Mechanisms of Action to Field Applications. Leonardo F. Fraceto, Hudson W. P. de Carvalho, Renata de Lima,Subhasis Ghoshal, Catherine Santaella (Eds.). Springer Nature, Cham, Switzerland, 2022, Chapter 10, pp. 295-361. [ISBN 978-3-030-94154-3] (118.2 standard pages) 

Králová K, and Jampílek J. Phytoremediation of environmental matrices contaminated with photosystem II-inhibiting herbicides. In: Pesticide Bioremediation. Sazada Siddiqui, Mukesh Kumar Meghvansi, Kamal Kishore Chaudhary (Eds.). Springer Nature, Cham, Switzerland, 2022, Chapter 2, pp. 31-80. [ISBN 978-3-030-96999-8] (87.9 standard pages) 

Matušková V, Zatloukal M, Pospíšil T, Voller J, Vylíčilová H, Doležal K, Strnad M. From synthesis to the biological effect of isoprenoid 2′-deoxyriboside and 2′,3′-dideoxyriboside cytokinin analogues. Phytochemistry 2023;205:113481.

Olarewajua OO, Magwaza LS, Fajinmi OO, Fawole OA, Plačková L, Doležal K.: Changes in cytokinins and auxins levels in the rind of ‘Nules Clementine’ mandarin as related to the fruit position on the tree and the susceptibility to non-chilling rind breakdown disorder. South African Journal of Botany 151, 667-674, 2022.

Parizkova B, Antoniadi I, Poxson DJ, Karady M, Simon DT, Zatloukal M, Strnad M, Dolezal K, Novak O, Ljung K. Cytokinin Micro Application Modulates Root Development with High Spatial Resolution, Advanced Materials Technologies, 2022, DOI: 10.1002/admt.202101664

Pilařová V, Kuda L, Vlčková HK, Nováková L, Gupta S, Kulkarni M, Švec F, Van Staden J, Doležal K. Carbon dioxide expanded liquid: an effective solvent for the extraction of quercetin from South African medicinal plants. Plant Methods. 2022 Jun 23;18(1):87. doi: 10.1186/s13007-022-00919-6. PMID: 35739596; PMCID: PMC9219150 (IF₂₀₂₁ = 5.827)

Pindjaková D, Pilařová E, Pauk K, Michnová H, Hošek J, Magar P, Čížek A, Imramovský A, Jampílek J. Study of Biological Activities and ADMET-Related Properties of Salicylanilide-Based Peptidomimetics. Int. J. Mol. Sci. 2022, vol. 23, no. 19, 11648, https://www.mdpi.com/1422-0067/23/19/11648/pdf. [ISSN 1422-0067, IF₂₀₂₁ = 6.208, Q1]

Razmienė, B., Vojáčková, V., Řezníčková, E., Malina, L., Dambrauskienė, V., Kubala, M., Bajgar, R., Kolářová, H., Žukauskaitė, A., Arbačiauskienė, E., Šačkus, A., Kryštof, V. (2022) Synthesis of N-aryl-2,6-diphenyl-2H-pyrazolo[4,3-c]pyridin-7-amines and their photodynamic properties in the human skin melanoma cell line G361. Bioorganic Chemistry, 119, 105570. (IF₂₀₂₀ = 5.275) https://doi.org/10.1016/j.bioorg.2021.105570

Supikova K, Kosinova A, Vavrusa M, Koplikova L, François A, Pospisil J, Zatloukal M, Wever R, Hartog A, Gruz J (2022) Sulfated phenolic acids in plants. Planta. 255(6), 124. DOI: 10.1007/s00425-022-03902-6 (IF₂₀₂₁ = 4.689)

Široká J, Brunoni F, Pěnčík A, Mik V, Žukauskaitė A, Strnad M, Novák O, Floková K. High-throughput interspecies profiling of acidic plant hormones using miniaturised sample processing. Plant Methods, 18, 122 (2022). https://doi.org/10.1186/s13007-022-00954-3 

Vostálová J, Škařupová D, Plíhalová L, Hönig M, Zálešák B, Rajnochová-Svobodová A. Photoprotective properties of new derivatives of kinetin. Photochem Photobiol Sci. 2022 Oct 20. doi: 10.1007/s43630-022-00320-1.

2021

Aremu, A. O., Plackova, L., Egbewale, S.O.,  Doležal, K., Magadlela, A.: Soil nutrient status of KwaZulu-Natal savanna and grassland biomes causes variation in cytokinin functional groups and their levels in above-ground and underground parts of three legumes. Physiology and Molecular Biology of Plants 27 (6), 1337-1351, 2021.

Ameztoy, K., Sanchez-Lopez, A. M., Munoz, F. J., Bahaji, A., Almagro, G., Baroja-Fernandez, E., Gamez-Arcas, S., De Diego, N., Doležal, K., Novák, O., Pěnčík, A., Alpizar, A., Rodriguez-Concepcion, M., Pozueta-Romero, J.: Proteostatic Regulation of MEP and Shikimate Pathways by Redox-Activated Photosynthesis Signaling in Plants Exposed to Small Fungal Volatiles. Frontiers in Plant Science 12: 637976, 2021.

Baroja-Fernandez, E., Almagro, G., Sanchez-Lopez, A.M., Bahaji, A.,  Gamez-Arcas, S., De Diego, N., Doležal, K., Munoz, F.J., Sanz, E.C.,  Pozueta-Romero, J.: Enhanced Yield of Pepper Plants Promoted by Soil Application of Volatiles From Cell-Free Fungal Culture Filtrates Is Associated With Activation of the Beneficial Soil Microbiota. Frontiers in Plant Science 12: 752653, 2021.

Bíbová J., Zatloukal M., Koprna R., Spíchal L., Strnad M., New Generation of Arabidopsis thaliana Cytokinin oxidase/Dehydrogenase inhibitors Affect Shoot/Root Growth and Seed Yield In Meta-topolin: A Growth Regulator for Plant Biotechnology and Agriculture. Springer Nature Singapore Pte Ltd. 2021, s. 293-316. ISBN 978-981-15-9046-7.

Doležal K., Bryksová M., Topolin Metabolism and Its Implications for In Vitro Plant Micropropagation In Meta-topolin: A Growth Regulator for Plant Biotechnology and Agriculture. Springer Nature Singapore Pte Ltd. 2021, s. 49-58. ISBN 978-981-15-9046-7.

Empel A. and Bak A., Kozik V., Latocha M., Čížek A., Jampílek J., Suwinska K., Sochanik A., Zieba A. Towards Property Profiling: Synthesis and SAR Probing of New Tetracyclic Diazaphenothiazine Analogues. Int. J. Mol. Sci. 2021, vol. 22, no. 23, 12826. (IF = 5.923) https://www.mdpi.com/1422-0067/22/23/12826/pdf

Gupta, S, Stirk, W.A., Plačková, L., Kulkarni, M.G., Doležal, K., Van Staden, J.: Interactive effects of plant growth-promoting rhizobacteria and a seaweed extract on the growth and physiology of Allium cepa L. (onion). Journal of Plant Physiology 262, 153437, 2021.

Hrdlička J., Gucký T., Van Staden J., Novák O., Doležal K. (2021) A stable isotope dilution method for a highly accurate analysis of karrikins. Plant Methods, 17, 37. (IF = 3.974) https://doi.org/10.1186/s13007-021-00738-1

Hemelíková, N., Žukauskaitė, A., Pospíšil, T., Strnad, M., Doležal, K., Mik, V. (2021) Caged phytohormones: from chemical inactivation to controlled physiological response. Journal of Agricultural and Food Chemistry, 69, 12111. (IF = 5.279) https://doi.org/10.1021/acs.jafc.1c02018

Iškauskienė M., Kadlecová A., Voller J., Janovská L., Malinauskienė V., Žukauskaitė A., Šačkus A. (2021) Synthesis of 5-[(1H-indol-3-yl)methyl]-1,3,4-oxadiazole-2(3H)-thiones and their protective activity against oxidative stress. Archiv der Pharmazie, 354, e2100001. (IF = 3.751) https://doi.org/10.1002/ardp.202100001

Koprna R., Humplík J.F., Špíšek Z., Bryksová M., Zatloukal M., Mik V., Novák O., Nisler J., Doležal K. (2021) Improvement of tillering and grain yield by application of cytokinin derivatives in wheat and barely. Agronomy, 11, 67. ( IF=2.603) https://doi.org/10.3390/agronomy11010067

Koprna R., Zatloukal M., Doležal K., Topolins and Related Compounds: Uses in Agriculture In Meta-topolin: A Growth Regulator for Plant Biotechnology and Agriculture. Springer Nature Singapore Pte Ltd. 2021, s. 317-328, ISBN 978-981-15-9046-7.

Ochedzan-Siodlak, W., Siodlak, D., Banas, K.,  Halikowska, K.,  Wierzba, S.,  Doležal, K.: Naturally Occurring Oxazole Structural Units as Ligands of Vanadium Catalysts for Ethylene-Norbornene (Co)polymerization. Catalyst 11 (8), 923, 2021.

Pařízková B., Žukauskaitė A., Vain T., Grones P., Raggi S., Kubeš M.F., Kieffer M., Doyle S.M., Strnad M., Kepinski S., Napier R., Doležal K., Robert S., Novák O. (2021) New fluorescent auxin probes visualise tissue-specific and subcellular distributions of auxin in Arabidopsis. New Phytologist, 230, 535. (IF = 10.152) https://doi.org/10.1111/nph.171833

Plíhalová L., Synthesis and Chemistry of Meta-Topolin and Related Compounds In: Meta-topolin: A Growth Regulator for Plant Biotechnology and Agriculture. Springer Nature Singapore Pte Ltd. 2021, s. 11-22 ISBN 978-981-15-9046-7.

Pospíšil, J.; Konrádová, D.; Strnad, M.,Antileishmanial Activity of Lignans, Neolignans, and Other Plant Phenols. In Progress in the Chemistry of Organic Natural Products 115; Springer International Publishing, 2021; pp 115–176. https://doi.org/10.1007/978-3-030-64853-4_3

Razmienė, B., Řezníčková, E., Dambrauskienė, V., Ostruszka, R., Kubala, M., Žukauskaitė, A., Kryštof, V., Šačkus, A., Arbačiauskienė, E. Synthesis and antiproliferative activity of 2,4,6,7-tetrasubstituted-2H-pyrazolo[4,3-c]pyridines. Molecules, 26, 6747. (IF = 4.412) https://doi.org/10.3390/molecules26216747

Samakovli, D., Roka, L., Dimopoulou, A., Plitsi, P.K., Žukauskaitė, A., Georgopoulou P., Novák, O., Milioni, D., Hatzopoulos, P. (2021) HSP90 affects root growth in Arabidopsis by regulating the polar distribution of PIN1. New Phytologist, 231, 1814. (IF = 10.152) https://doi.org/10.1111/nph.17528

Zálešák F., Kováč O., Lachetová E., Šťastná N., Pospíšil J. (2021) Unified Approach to Benzo[d]thiazol-2-yl-Sulfonamides. Journal of Organic Chemistry 86(17): 11291–11309. (IF = 4.354) DOI: 10.1021/acs.joc.1c00317

Zhang C., Žukauskaitė A., Petřík I., Pěnčík A., Hönig M., Grúz J., Široká J., Novák O., Doležal K. (2021) In situ characterisation of phytohormones from wounded Arabidopsis leaves using desorption electrospray ionisation mass spectrometry imaging. Analyst, 146, 2653. (IF = 4.616) https://doi.org/10.1039/D0AN02118K

 

2020

Antoniadi I., Novák O., Gelová Z., Johnson A., Plíhal O., Simerský R., Mik V., Vain T., Mateo-Bonmatí E., Karady M., Pernisová M., Plačková L., Opassathian K., Hejátko J., Robert S., Friml J., Doležal K., Ljung K., Turnbull C. (2020) Cell-surface receptors enable perception of extracellular cytokinins. Nature Communications, 11, 4284. (IF = 12.121) https://doi.org/10.1038/s41467-020-17700-9

Aremu A.O., Fawole O.A., Makunga N.P., Masondo N.A., Moyo M., Buthelezi N.M.D., Amoo S.O., Spíchal L., Doležal K. (2020) Applications of cytokinins in horticultural fruit crops: Trends and future prospects. Biomolecules, 10, 1222. (IF = 4.694) https://doi.org/10.3390/biom10091222

Bryksová M., Dabravolski S., Kučerová Z., Zavadil Kokáš F., Špundová M., Plíhalová L., Takáč T., Grúz, J., Hudeček M., Hlousková V., Koprna R., Novák O., Strnad M., Plíhal O., Doležal K. (2020) Aromatic cytokinin arabinosides promote PAMP-like responses and positively regulate leaf longevity. ACS Chemical Biology, 15, 1949. (IF = 4.434) https://doi.org/10.1021/acschembio.0c00306

Bryksová M., Hybenová A., Hernandíz A.E., Novák O., Pěnčík A., Spíchal L., De Diego N., Doležal K. (2020) Hormopriming to migrate abiotic stress effects: A case study of N⁹-substituted cytokinin derivatives with a fluorinated carbohydrate moiety. Frontiers in Plant Science, 11, 599228. (IF = 4.402) https://doi.org/10.3389/fpls.2020.599228

Gupta S., Hrdlička J., Ngoroyemoto N., Nemahunguni N.K., Gucký T., Novák O., Kulkarni M.G., Doležal K., Van Staden J. (2020) Preparation and standardisation of smoke-water for seed germination and plant growth stimulation. Journal of Plant Growth Regulation, 39, 338. (IF = 2.672) https://doi.org/10.1007/s00344-019-09985-y

Hlatshwayo N.A., Amoo S.O., Olowoyo J.O., Doležal K. (2020) Efficient micropropagation protocol for the conservation of the endangered Aloe peglerae, an ornamental and medicinal species. Plants, 9, 506. (IF = 3.182) https://doi.org/10.3390/plants9040506

Hlophe N.P., Aremu A.O., Doležal K., Van Staden J., Finnie J.F. (2020) Cytokinin-facilitated plant regeneration of three Brachystelma species with different conservation status. Plants, 9, 1657. (IF = 3.182) https://doi.org/10.3390/plants9121657

Kováč O., Zálešák F., Bon D.J.-Y.D., Roiser L., Baar L.V., Waser M., Pospíšil J. (2020) Trisubstituted highly activated benzo[d]thiazol-2-yl-sulfone-containing olefins as building blocks in organic synthesis. Journal of Organic Chemistry, 85, 7192. (IF = 4.335) https://doi.org/10.1021/acs.joc.0c00571

Králová P., Maloň M., Pospíšil J., Soural M. (2020) Rearrangement of threonine and serine-based N-(3-phenylprop-2-yn-1-yl) sulfonamides yields chiral pyrrolidin-3-ones. Journal of Organic Chemistry, 5, 985. (IF = 4.335) https://doi.org/10.1021/acs.joc.9b02932

Kubiasová K., Montesinos J.C., Šamajová O., Nisler J., Mik V., Semerádová H., Plíhalová L., Novák O., Marhavý P., Cavallari N., Zalabák D., Berka K., Doležal K., Galuszka P., Šamaj J., Strnad M, Benková E., Plíhal O., Spíchal L. (2020) Cytokinin fluoroprobe reveals multiple sites of cytokinin perception at plasma membrane and endoplasmic reticulum. Nature Communications, 11, 4285. (IF = 13.610) https://doi.org/10.1038/s41467-020-17949-0

Kučerová Z., Rác M., Mikulík J., Plíhal O., Pospíšil P., Bryksová M., Sedlářová M., Doležal K., Špundová M. (2020) The anti-senescence activity of cytokinin arabinosides in wheat and Arabidopsis in negatively correlated with ethylene production. International Journal of Molecular Sciences, 21, 8109. (IF = 5.556) https://doi.org/10.3390/ijms21218109

Mathieu A.S., Dobrev P.I., Tarkowská D., Pospíšil J., Motyka V., Quinet M., Lutts S. (2020) Phytohormone profile and CiFL1 expression in young seedlings of Cichorium intybus L. var sativum exposed to high temperature in relation to vernalization and de-vernalization processes. Enviromental and Experimental Botany, 178, 104127. (IF = 4.027) https://doi.org/10.1016/j.envexpbot.2020.104127

Matušková V., Zatloukal M., Voller J., Grúz J., Pěkná Z., Briestenská K., Mistríková J., Spíchal L., Doležal K., Strnad M. (2020) New aromatic 6-substituted 2 '-deoxy-9-β-D-ribofuranosylpurine derivatives as potential plant growth regulators. Bioorganic & Medicinal Chemistry, 28, 115230. (IF = 3.073) https://doi.org/10.1016/j.bmc.2019.115230

Milišiūnaitė V., Kadlecová A., Žukauskaitė A., Doležal K., Strnad M., Voller J., Arbačiauskienė E., Holzer W., Šačkus A. (2020) Synthesis and anthelmintic activity of benzopyrano[2,3-c]pyrazol-4(2H)-one derivatives. Molecular Diversity, 24, 1025. (IF = 2.013) https://doi.org/10.1007/s11030-019-10010-3

Nisler J., Kopečný D., Pěkná Z., Končitíková R., Koprna R., Murvanidze N., Werbrouck S.P.O., Havlíček L., De Diego N., Kopečná M., Wimmer Z., Biozzo P., Moréra S., Zalabák D., Spíchal l., Strnad M. (2020) Diphenylurea-derived cytokinin oxidase/dehydrogenase inhibitors for biotechnology and agriculture. Journal of Experimental Botany, 72, 355. (IF = 5.908) https://doi.org/10.1093/jxb/eraa437

Omoarelojie L.O., Kulkarni M.G., Finnie J.F., Pospíšil T., Strnad M., Van Staden J. (2020) Synthetic strigolactone (rac-GR24) alleviates the adverse effects of heat stress on seed germination and photosystem II function in lupine seedlings. Plant Physiology and Biochemistry, 155, 965. (IF = 3.720) https://doi.org/10.1016/j.plaphy.2020.07.043

Pospíšil, J. 1-(Phenylsulfonyl)-3-oxabicyclo[3.1.0]hexan-2-one” Pospíšil, J. In Encyclopedia of Reagents for Organic Synthesis; Major Reference Works; Wiley Online Library, New Jersey, 2020, pp 1–4. https://doi.org/10.1002/047084289X.rn02295

Šachlevičiūtė U., Varvuolytė G., Bieliauskas A., Kleizienė N., Žukauskaitė A., Šačkus A. (2020) 3,3,3′,3′-Tetramethyl-2,2′-diphenyl-3H,3′H-5,5′-biindole. Molbank, 1146, 1. (IF = 0.450) https://doi.org/10.3390/M1146

Tan S., Abas M., Verstraeten I., Glanc M., Molnár G., Hajný J., Lasák P., Petřík I., Russinova E., Petrášek J., Novák O., Pospíšil J., Friml J. (2020) Salicylic acid targets protein phosphatase 2A to attenuate growth in plants. Current Biology, 30, 381. (IF = 9.601) https://doi.org/10.1016/j.cub.2019.11.058

Vacek J., Zatloukalová M., Vrba J., De Vleeschouwer F., De Proft F., Obluková M., Sokolová R., Pospíšil J (2020) Diferulate: A highly effective electron donor. Journal of Electroanalytical Chemistry, 869, 113950. (IF = 3.807) https://doi.org/10.1016/j.jelechem.2020.113950

Varvuolytė G., Malina L., Bieliauskas A., Hošíková B., Simerská H., Kolářová H., Kleizienė N., Kryštof V., Šačkus A., Žukauskaitė A (2020) Synthesis and photodynamic properties of pyrazole-indole hybrids in the human skin melanoma cell line G361. Dyes and Pigments, 183, 108666. (IF = 4.613) https://doi.org/10.1016/j.dyepig.2020.108666

Vylíčilová H., Bryksová M., Matušková V., Doležal K., Plíhalová L., Strnad M. (2020) Naturally occurring and artificial N9-cytokinin conjugates: from synthesis to biological activity and back. Biomolecules, 10, 832. (IF = 4.694) https://doi.org/10.3390/biom10060832

Patenty

2024

EP 4153592: Klos D, Plíhalová L, Zatloukal M, Doležal K, Koprna R, Strnad M, Balonová J, Walla J. Mesylate salts of heterocyclic cytokinins, compositions containing these derivatives and use thereof.

EP 3229771: Doležal K, Plíhalová L, Vylíčilová H, Bryksová M, Zatloukal M, Strnad M, Plíhal O, Voller J, Ulrichová J, Vostálová J, Rajnochová-Svobodová A. 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF

EP 3924353: Strnad M, Gonzales G, Bucharová(Hemelíková) N, Mik V, Grúz J, Zatloukal M. HETEROCYCLIC NITROGEN-CONTAINING PURINE DERIVATIVES, PHARMACEUTICAL
PREPARATIONS CONTAINING THESE DERIVATIVES AND THEIR USE IN NEUROPROTECTION

CZ 310053: Rárová L, Mik V, Doležal K, Zatloukal M, Strnad M, Novák O. Heterocyklické purinové deriváty cytokininů, jejich použití při hojení ran a
farmaceutické kompozice obsahující tyto deriváty

2023

EP 4107145B1: Varvuolytė G, Malina V, Bieliauskas A, Hošíková B, Simerská H, Kolářová H, Kleizienė N, Strnad M, Arbačiauskienė E, Kryštof V, Šačkus A, Žukauskaitė A: Pyrazole-indole conjugates for photodynamic treatment of cancer and bacterial infections (02/08/2023).

2022

EP 3341371 - Hönig M, Plihalová L, Doležal K, Voller J, Strnad M, Spíchal L, Vostálová J, Rajnochová Svobodová A, Ulrichová J, Kadlecová A, Plíhal O. Adenine derivatives and their use as UV-photoprotective agents

EP 3615535A1 – Bíbová J, Mik V, Zatloukal M, Plíhalová L, Grúz J, Spíchal L, Doležal K, Strnad M. 9-(2-oxacycloalkyl)-9H-purine-2,6-diamine Derivatives and their use for the treatment of skin disorders

CZ 309368: Klos D, Plíhalová L, Zatloukal M, Doležal K, Koprna R, Strnad M, Walla J, Balonová J. Mesylátové soli heterocyklických cytokininů, přípravky obsahující tyto deriváty a jejich použití

2021

CZ 309070: Varvuolyté G, Malina V, Bieliauskas A, Hošíková B, Simerská H, Kolářová H, Kleiziené N, Strnad M, Arbačiauskiené E, Kryštof V, Šačkus A, Žukauskaitė A: Pyrazole-indole conjugates for the photodynamic treatment of cancer and bacterial infections (01/12/2021).

CZ 308881: Doležal K, Plíhalová L, Vylíčilová H, Zatloukal M, Plíhal O, Voller J, Strnad M: 6-aryl-9-glykosylpurines and use thereof, UPOL (23/6/2021).

CZ 308800: Gonzales, Mik, Bucharová, Grúz, Kaňovský, Strnad, Zatloukal: Heterocyclic nitrogen derivatives of purine, pharmaceutical preparations containing thouse derivatives and their neuroprotective application (14/4/2021)

WO 2021233486A1: Plíhalová L, Zatloukal M, Doležal K, Strnad M, Walla J, Voller J: Mesylate salt of para-topolin, compositions containing said salt and use thereof.

2020

US 10774084: Adenine derivatives and their use as UV-photoprotective agents, UPOL, Hönig M, Plíhalová L, Doležal K, Voller J, Strnad M, Spíchal L, Vostálová J, Rajnochová Svobodová A, Ulrichová J, Kadlecová A, Plíhal O, granted: 15/9/2020

US 10550144: 6-aryl-9-glykosylpurines and use thereof, UPOL, Doležal K, Plíhalová L, Vylíčilová H, Zatloukal M, Plíhal O, Voller J, Strnad M, Van Staden Johannes, Ponnusamy Baskaran, Aloka Kumari, Adeyemi Oladapo Aremu, granted: 4/2/2020

US 10662194: Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress, UPOL, Zatloukal M, Plíhalová L, Klásková J, Spíchal L, Koprna R, Doležal K, Strnad M, granted: 26/5/2020

EP 3229772: 6-aryl-9-glycosylpurines and use thereof, UPOL, Doležal K, Plíhalová L, Vylíčilová H, Zatloukal M, Plíhal O, Voller J, Strnad M, Van Staden J, Baskaran P, Kumari A, Aremu AO, granted: 29/4/2020

EP3233860: Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress, Zatloukal M, Plíhalová L, Klásková J, Spíchal L, Koprna R, granted. 29/1/2020

SG 11201704019T: 6-aryl-9-glykosylpurines and use thereof, Doležal K, Plíhalová L, Vylíčilová H, Zatloukal M, Plíhal O, Voller J, Strnad M, Bryksová M, Vostálová J, Rajnochová Svobodová A, Ulrichová J, Spíchal L, granted: 24/6/2020

2019

CZ307868: 9- (2-Oxacycloalkyl) -9H-purine-2,6-diamine derivatives, preparations containing these derivatives and their use, Bíbová J, Mik V, Zatloukal M, Plíhalová L, Grúz J, Spíchal L, Doležal K, Strnad M, granted: 29/5/2019.

CZ307722: Adenine derivatives and their use as UV-photoprotective agents/ Adeninové deriváty a jejich použití, Honig M, Plíhalová L, Doležal K, Voller J, Strnad M, Spíchal L, Vostálová J, Rajnochová Svobodová A, Ulrichová J, Kadlecová A, Plíhal O, granted: 13/2/2019

2018

US10100077: 6-aryl-9-glycosylpurines and use thereof, Doležal K, Plíhalová L, Vylíčilová H, Zatloukal M, Plíhal O, Voller J, Strnad M, Bryksová M, Vostálová J, Rajnochová Svobodová A, Ulrichová J, Spíchal L, granted: 2018.

US10093675: 6,8-disubstituted-9-(heterocyclyl)purines, compositions containing these derivatives and their use in cosmetic and medicinal applications, Zahajská L, Nisler J, Kadlecová A, Zatloukal M, Grúz J, Voller J, Doležal K, Strnad M, granted: 2018.

Registrace rostlinných přípravků

Aucyt Start (2018) – pomocný rostlinný přípravek, registrant – ÚKZÚZ, evidenční číslo R9445, registrační číslo: 4615.

Salis (2019) – pomocný rostlinný přípravek, registrant – ÚKZÚZ, evidenční číslo R10222, registrační číslo: 4672.

VegetUP (2020) – pomocný rostlinný přípravek, registrant – ÚKZÚZ, evidenční číslo R10345, registrační číslo: 4988.